Digestive Enzymes


Enzymes are digestion’s little helpers

Enzymes are digestion’s little helpers. Digestive enzymes speed up and facilitate the breakdown of food, allowing nutrients to be released and readily absorbed in your gut. In other words, they increase nutrient bioavailability, so you can get the most out of the food you eat.(1)

There are two kinds of digestive enzymes: those produced by your body and those that you get through diet. In your body, enzymes are found in the mouth, stomach, and small intestine, but the majority are released from the pancreas. When activated by the presence of food, these enzymes flood out of your pancreas and into your small intestine. In the diet, digestive enzymes are found in plant-based foods.

Here are some digestive enzymes and what each one breaks down: 

Amylase & glucoamylase


Protease, bromelain & papain








Invertase & maltase


Poor enzyme production or utilization results in insufficient nutrient absorption and deficiency. In the long-term, this can cause significant damage to core gut architecture (the actual anatomy of the gut), leading to discomfort and a whole host of serious health issues.(2)  Supplementing with digestive enzymes can be beneficial if your natural enzyme production is insufficient or if you are not getting enough from your diet. If you fall into any of the categories below, increasing your digestive enzyme intake may help you take control of your health and heal your gut.

  • People who are overweight, obese, or have diabetes: We live in an environment that encourages a sedentary lifestyle and a high caloric intake, so it’s no wonder the prevalence of obesity in the United States was 42.4% in 2018.(3)  Studies conducted worldwide have shown a link between chronic diseases, obesity, and the bioavailability and utilization of nutrients.(4)  The negative impact of diabetes and obesity on the production of digestive enzymes creates long-term diminishing utilization of vital nutrients.

  • Vegetarians and vegans: Vegetarian and vegan diets have many health benefits. However, formulating a diet completely free of animal protein requires some research and planning. If you’re not careful, it can be easy to become protein-deficient. That can harm your digestion by negatively affecting your pancreas. Healthy protein and complete amino acid consumption are essential in promoting enzyme secretion via the pancreas.(5) Studies show that protein deficiency can impair pancreatic function. Regardless of your diet, if you’re having trouble meeting your protein needs, you might consider supplementing with digestive enzymes.

  • Excessive alcohol intake is defined as more than three drinks a day or seven drinks per week for women, and more than four drinks a day or 14 drinks per week for men.(6) Heavy drinking has been shown to significantly harm pancreatic function. Excessive alcohol damages pancreatic ducts, which secrete enzymes throughout the body. Instead of being released into the digestive tract, enzymes begin to build up in the pancreas and break down that essential organ itself.(7)

  • Use of long-term antibiotics: Antibiotics are a standard treatment for bacterial infection and can be lifesaving. However, they are also over-prescribed. The most common side effects of antibiotics are associated with the digestive system, including nausea, vomiting, abdominal pain, and diarrhea.(8)  This may be partially explained by a 2017 study on the effects of antibiotics on nutrient digestion, which showed these medications impair the release and activation of digestive enzymes.(9)

  • Physical, emotional, or psychological stress: Chronic stress can put your body in a heightened state of defense, which means that basic functions like digestion are not getting the attention they need to function properly. This can cause reduced release of digestive enzymes, leading to stomach pain and poor health.(10)

If you are experiencing any of the symptoms below, that may be an indication that you’re not digesting your food properly, which can potentially damage your core gut architecture.(11)

Signs your digestion is impaired?

  • You experience abdominal pain and cramps after eating
  • You frequently have heartburn or acid indigestion 
  • You often feel bloated 
  • You often have gas (burps and/or flatulence) 
  • You suffer from occasional constipation and/or diarrhea 

Digestive Enzymes in Previlli

Previlli™ contains digestive enzymes from plants that help break down all components of food: proteins, carbohydrates, starches, fats, fiber, and sugar.* Not only do these digestive enzymes support enhanced nutrient absorption, but they can prevent further insult to your gut wall.* That’s because complete breakdown of these food components means less irritation of your gut lining.*

How digestion is influenced by gut architecture

  • The lining of your gut senses nutrients, toxins, and waste and manages what gets absorbed and what gets eliminated.
  • Gut permeability impairs the ability of your gut lining to properly sense and manage digestion. 
  • Gut permeability reduces the efficiency of digestion and causes irritation. 
  • Your microvilli influence nutrient absorption, gut motility (how fast food moves through your system), immune function, and metabolism. 
  • Mucin (the sticky protective covering of the gut lining) helps manage good and bad bacteria. 

In addition to supporting digestive balance with its Activated Enzyme Blend, Previlli™ also supports gut architecture and overall gut health, making your gut a happy, healthy place to be.* 

1. https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5951603/ 
2. https://www.ncbi.nlm.nih.gov/books/NBK553106/ 
3. https://www.cdc.gov/obesity/data/adult.html 
4. https://pubmed.ncbi.nlm.nih.gov/32377370/ 
5. https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2739082/ 
6. https://pubs.niaaa.nih.gov/publications/aa22.htm 
7. https://americanaddictioncenters.org/alcoholism-treatment/effects-of-alcohol-on-the-pancreas 
8. https://www.emerginginvestigators.org/articles/the-effects-of-antibiotics-on-nutrient-digestion/pdf 
9. https://www.frontiersin.org/articles/10.3389/fmicb.2018.02427/full 
10. https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3341916/
11. https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6249666/